Express Scripts to lay off 227 in Fort Worth

Express Scripts Inc., the nation’s largest pharmacy benefit manager, will lay off 227 wokers at a facility in the Fossil Creek Business Park, according to a WARN letter sent to the Texas Workforce Commission.

The company is closing a pharmacy at 5450 N. Riverside Dr. in Fort Worth.

Last year the company laid off more than 560 employees in its offices in Fort Worth and Irving, and closed a prescription processing facility in east Fort Worth.

Express Scripts acquired Medco Health Solutions for $29 billion in 2012, making it the nation’s biggest pharmacy benefit manager, but in 2013 it lost United Healthcare, a major client.